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On the other hand, in a more recent study, the same authors of the prior RCT found that preoperative TPO-Ab levels did not appear to influence the odds ratio to obtain a clinically significant improvement in QoL, which might not fully support the hypothesis of autoimmunity being directly responsible for persistent symptoms in patients with euthyroid HT (56)

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Armamentarium of cryoprotectants in peptide vaccines : mechanistic insight, challenges , opportunities and future prospects